產(chǎn)品詳情
簡單介紹:
Prasugrel
詳情介紹:
Purpose | Prasugrel, a thienopyridine derivative, is a platelet activation and aggregation inhibitor structurally and pharmacologically related to clopidogrel and ticlopidine. Similar to clopidogrel, prasugrel is a prodrug that requires enzymatic transformation in the liver to its active metabolite, R-138727. R-138727 irreversibly binds to P2Y12 type ADP receptors on platelets thus preventing activation of the GPIIb/IIIa receptor complex. As a result, inhibition of ADP-mediated platelet activation and aggregation occurs. Prasugrel was developed by Daiichi Sankyo Co. and is currently marketed in the United States and Canada in cooperation with Eli Lilly and Company for acute coronary syndromes planned for percutaneous coronary intervention (PCI). FDA approved in 2009. |
Characteristics |
Tradename: EFFIENT Source of Compound: synthetic Target: P2 Receptor antagonist Receptor: Cocaine esterase, P2Y Receptor Status: USAN, INN |
Purification | All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality. |
Purity | 99?% |
Formula | C20H20FNO3S |
Solubility | In water, 20.28 mg/L |
Molecular Weight | 373.44 g/mol |
CAS-No | 150322-43-3 |
Application Notes | Optimal working dilution should be determined by the investigator. |
Restrictions | For Research Use only |
Format | Solid |
Storage | -20 °C |
Storage Comment |
For the majority of compounds, they could be dissolved in DMSO or other organic solvent. Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience. Several freeze/thaw cycles should not damage the activity of our small molecule products. However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours. |
Expiry Date | 24 months |